Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons

Mitochondria are present as tubular organelles in neuronal projections. Here, we report that mitochondria undergo profound fission in response to nitric oxide (NO) in cortical neurons of primary cultures. Mitochondrial fission by NO occurs long before neurite injury and neuronal cell death. Furtherm...

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Detalhes bibliográficos
Main Authors: Barsoum, Mark J, Yuan, Hua, Gerencser, Akos A, Liot, Géraldine, Kushnareva, Yulia, Gräber, Simone, Kovacs, Imre, Lee, Wilson D, Waggoner, Jenna, Cui, Jiankun, White, Andrew D, Bossy, Blaise, Martinou, Jean-Claude, Youle, Richard J, Lipton, Stuart A, Ellisman, Mark H, Perkins, Guy A, Bossy-Wetzel, Ella
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1553198/
https://ncbi.nlm.nih.gov/pubmed/16874299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601253
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