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Purification, crystallization and X-ray diffraction analysis of human dynamin-related protein 1 GTPase-GED fusion protein

The mechano-enzyme dynamin-related protein 1 plays an important role in mitochondrial fission and is implicated in cell physiology. Dysregulation of Drp1 is associated with abnormal mitochondrial dynamics and neuronal damage. Drp1 shares structural and functional similarities with dynamin 1 with res...

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Detalhes bibliográficos
Main Authors: Klinglmayr, Eva, Wenger, Julia, Mayr, Sandra, Bossy-Wetzel, Ella, Puehringer, Sandra
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497983/
https://ncbi.nlm.nih.gov/pubmed/23027751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S174430911203607X
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