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Nef Enhances Human Immunodeficiency Virus Type 1 Infectivity and Replication Independently of Viral Coreceptor Tropism

We investigated the infectivities and replicative capacities of a large panel of variants of the molecular human immunodeficiency virus type 1 (HIV-1) NL4-3 clone that differ exclusively in the V3 region of the viral envelope glycoprotein and the nef gene. Our results demonstrate that Nef enhances v...

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Detalles Bibliográficos
Main Authors: Papkalla, Armin, Münch, Jan, Otto, Claas, Kirchhoff, Frank
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC155138/
https://ncbi.nlm.nih.gov/pubmed/12134048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.16.8455-8459.2002
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