The Simian Immunodeficiency Virus Δnef Vaccine, after Application to the Tonsils of Rhesus Macaques, Replicates Primarily within CD4(+) T Cells and Elicits a Local Perforin-Positive CD8(+) T-Cell Response

Deletion of the nef gene from simian immunodeficiency virus (SIV) strain SIVmac239 yields a virus that undergoes attenuated growth in rhesus macaques and offers substantial protection against a subsequent challenge with some SIV wild-type viruses. We used a recently described model to identify sites...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Stahl-Hennig, Christiane, Steinman, Ralph M., Ten Haaft, Peter, Überla, Klaus, Stolte, Nicole, Saeland, Sem, Tenner-Racz, Klara, Racz, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC136843/
https://ncbi.nlm.nih.gov/pubmed/11752159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.2.688-696.2002
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky