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The Simian Immunodeficiency Virus Δnef Vaccine, after Application to the Tonsils of Rhesus Macaques, Replicates Primarily within CD4(+) T Cells and Elicits a Local Perforin-Positive CD8(+) T-Cell Response
Deletion of the nef gene from simian immunodeficiency virus (SIV) strain SIVmac239 yields a virus that undergoes attenuated growth in rhesus macaques and offers substantial protection against a subsequent challenge with some SIV wild-type viruses. We used a recently described model to identify sites...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology
2002
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC136843/ https://ncbi.nlm.nih.gov/pubmed/11752159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.2.688-696.2002 |
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