T cell receptor gene deletion circles identify recent thymic emigrants in the peripheral T cell pool
Progenitor cells undergo T cell receptor (TCR) gene rearrangements during their intrathymic differentiation to become T cells. Rearrangements of the variable (V), diversity (D), and joining (J) segments of the TCR genes result in deletion of the intervening chromosomal DNA and the formation of circu...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1999
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15507/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9990059/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.4.1536 |
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