T cell receptor gene deletion circles identify recent thymic emigrants in the peripheral T cell pool

Progenitor cells undergo T cell receptor (TCR) gene rearrangements during their intrathymic differentiation to become T cells. Rearrangements of the variable (V), diversity (D), and joining (J) segments of the TCR genes result in deletion of the intervening chromosomal DNA and the formation of circu...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Kong, Fan-kun, Chen, Chen-lo H., Six, Adrien, Hockett, Richard D., Cooper, Max D.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15507/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9990059/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.4.1536
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