On the role of thymic epithelium vs. bone marrow-derived cells in repertoire selection of T cells
T lymphocytes mature in the thymus to become functional T cells. Studies with chimeric mice and T cell receptor (TCR) transgenic (tg) mice have indicated that the major histocompatibility gene complex (MHC) of thymic radio-resistant (presumed to be epithelial) cells positively select the MHC-restric...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22193/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10393953/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.14.8092 |
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