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T cell receptor gene deletion circles identify recent thymic emigrants in the peripheral T cell pool

Progenitor cells undergo T cell receptor (TCR) gene rearrangements during their intrathymic differentiation to become T cells. Rearrangements of the variable (V), diversity (D), and joining (J) segments of the TCR genes result in deletion of the intervening chromosomal DNA and the formation of circu...

詳細記述

保存先:
書誌詳細
主要な著者: Kong, Fan-kun, Chen, Chen-lo H., Six, Adrien, Hockett, Richard D., Cooper, Max D.
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences 1999
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC15507/
https://ncbi.nlm.nih.gov/pubmed/9990059
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