Lethal mutagenesis of HIV with mutagenic nucleoside analogs

The human immunodeficiency virus (HIV) replicates its genome and mutates at exceptionally high rates. As a result, the virus is able to evade immunological and chemical antiviral agents. We tested the hypothesis that a further increase in the mutation rate by promutagenic nucleoside analogs would ab...

Descrición completa

Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Loeb, Lawrence A., Essigmann, John M., Kazazi, Farhad, Zhang, Jue, Rose, Karl D., Mullins, James I.
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15492/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9990051/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.4.1492
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!