Lethal mutagenesis of HIV with mutagenic nucleoside analogs
The human immunodeficiency virus (HIV) replicates its genome and mutates at exceptionally high rates. As a result, the virus is able to evade immunological and chemical antiviral agents. We tested the hypothesis that a further increase in the mutation rate by promutagenic nucleoside analogs would ab...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1999
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15492/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9990051/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.4.1492 |
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