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Structural basis for antibiotic recognition by the TipA class of multidrug-resistance transcriptional regulators
The TipAL protein, a bacterial transcriptional regulator of the MerR family, is activated by numerous cyclic thiopeptide antibiotics. Its C-terminal drug-binding domain, TipAS, defines a subfamily of broadly distributed bacterial proteins including Mta, a central regulator of multidrug resistance in...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC154473/ https://ncbi.nlm.nih.gov/pubmed/12682015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg181 |
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