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Dynamic multidrug recognition by multidrug transcriptional repressor LmrR

LmrR is a multidrug transcriptional repressor that controls the expression of a major multidrug transporter, LmrCD, in Lactococcus lactis. However, the molecular mechanism by which LmrR binds to structurally unrelated compounds and is released from the promoter region remains largely unknown. Here,...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Takeuchi, Koh, Tokunaga, Yuji, Imai, Misaki, Takahashi, Hideo, Shimada, Ichio
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4235314/
https://ncbi.nlm.nih.gov/pubmed/25403615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06922
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