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Structural basis for human sterol isomerase in cholesterol biosynthesis and multidrug recognition
3-β-hydroxysteroid-Δ(8), Δ(7)-isomerase, known as Emopamil-Binding Protein (EBP), is an endoplasmic reticulum membrane protein involved in cholesterol biosynthesis, autophagy, oligodendrocyte formation. The mutation on EBP can cause Conradi-Hunermann syndrome, an inborn error. Interestingly, EBP bin...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6549186/ https://ncbi.nlm.nih.gov/pubmed/31165728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10279-w |
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