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Benefit of farnesoid X receptor inhibition in obstructive cholestasis

The nuclear hormone receptors farnesoid X receptor (FXR) and pregnane X receptor have been implicated in regulating bile acid, lipid, carbohydrate, and xenobiotic metabolism. Bile duct ligation was used to increase endogenous bile acids and evaluate the roles of these receptors in modulating cholest...

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Библиографические подробности
Главные авторы: Stedman, Catherine, Liddle, Christopher, Coulter, Sally, Sonoda, Junichiro, Alvarez, Jacqueline G., Evans, Ronald M., Downes, Michael
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2006
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544085/
https://ncbi.nlm.nih.gov/pubmed/16844773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604772103
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