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Benefit of farnesoid X receptor inhibition in obstructive cholestasis
The nuclear hormone receptors farnesoid X receptor (FXR) and pregnane X receptor have been implicated in regulating bile acid, lipid, carbohydrate, and xenobiotic metabolism. Bile duct ligation was used to increase endogenous bile acids and evaluate the roles of these receptors in modulating cholest...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1544085/ https://ncbi.nlm.nih.gov/pubmed/16844773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604772103 |
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