Intrahepatic Cholestasis of Pregnancy Levels of Sulfated Progesterone Metabolites Inhibit Farnesoid X Receptor Resulting in a Cholestatic Phenotype

Intrahepatic cholestasis of pregnancy (ICP) is the most prevalent pregnancy-specific liver disease and is associated with an increased risk of adverse fetal outcomes, including preterm labor and intrauterine death. The endocrine signals that cause cholestasis are not known but 3α-sulfated progestero...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Abu-Hayyeh, Shadi, Papacleovoulou, Georgia, Lövgren-Sandblom, Anita, Tahir, Mehreen, Oduwole, Olayiwola, Jamaludin, Nurul Akmal, Ravat, Sabiha, Nikolova, Vanya, Chambers, Jenny, Selden, Clare, Rees, Myrddin, Marschall, Hanns-Ulrich, Parker, Malcolm G, Williamson, Catherine
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Wiley Subscription Services, Inc., A Wiley Company 2013
Pynciau:
Autoimmune, Cholestatic and Biliary Disease
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592994/
https://ncbi.nlm.nih.gov/pubmed/22961653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26055
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