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The role of the ubiquitination–proteasome pathway in breast cancer: Ubiquitin mediated degradation of growth factor receptors in the pathogenesis and treatment of cancer

Aberrant activity of growth factor receptors has been implicated in the pathogenesis of a wide variety of malignancies. The negative regulation of signaling by growth factor receptors is mediated in large part by the ubiquitination, internalization, and degradation of the activated receptor. Over th...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Breast Cancer Res
Prif Awdur: Lipkowitz, Stan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMC 2002
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154127/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12559039/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/bcr541
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