Enzymatic blockade of the ubiquitin-proteasome pathway.
Ubiquitin-dependent processes control much of cellular physiology. We show that expression of a highly active, Epstein-Barr virus-derived deubiquitylating enzyme (EBV-DUB) blocks proteasomal degradation of cytosolic and ER-derived proteins by preemptive removal of ubiquitin from proteasome substrate...
Tallennettuna:
| Päätekijät: | , , , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Public Library of Science (PLoS)
2011-03-01
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| Sarja: | PLoS Biology |
| Linkit: | http://europepmc.org/articles/PMC3066133?pdf=render |
| Tagit: |
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