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The role of the ubiquitination–proteasome pathway in breast cancer: Ubiquitin mediated degradation of growth factor receptors in the pathogenesis and treatment of cancer
Aberrant activity of growth factor receptors has been implicated in the pathogenesis of a wide variety of malignancies. The negative regulation of signaling by growth factor receptors is mediated in large part by the ubiquitination, internalization, and degradation of the activated receptor. Over th...
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
BioMed Central
2003
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| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC154127/ https://ncbi.nlm.nih.gov/pubmed/12559039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr541 |
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