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The role of the ubiquitination–proteasome pathway in breast cancer: Use of mouse models for analyzing ubiquitination processes

Turnover of several regulatory proteins results from targeted destruction via ubiquitination and subsequent degradation through the proteosome. The timely and irreversible degradation of critical regulators is essential for normal cellular function. The precise biochemical mechanisms that are involv...

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Detalhes bibliográficos
Main Authors: Rossi, Sabrina, Loda, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC154128/
https://ncbi.nlm.nih.gov/pubmed/12559040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr542
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