Production of transmitochondrial cybrids containing naturally occurring pathogenic mtDNA variants

The human mitochondrial genome (mtDNA) encodes polypeptides that are critical for coupling oxidative phosphorylation. Our detailed understanding of the molecular processes that mediate mitochondrial gene expression and the structure–function relationships of the OXPHOS components could be greatly im...

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Detalhes bibliográficos
Main Authors: Pye, Deborah, Kyriakouli, Dimitra S., Taylor, Geoffrey A., Johnson, Riem, Elstner, Matthias, Meunier, Brigitte, Chrzanowska-Lightowlers, Zofia M. A., Taylor, Robert W., Turnbull, Douglass M., Lightowlers, Robert N.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2006
Assuntos:
Methods Online
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1540737/
https://ncbi.nlm.nih.gov/pubmed/16885236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl516
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