Production of transmitochondrial cybrids containing naturally occurring pathogenic mtDNA variants

The human mitochondrial genome (mtDNA) encodes polypeptides that are critical for coupling oxidative phosphorylation. Our detailed understanding of the molecular processes that mediate mitochondrial gene expression and the structure–function relationships of the OXPHOS components could be greatly im...

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Bibliographische Detailangaben
Hauptverfasser: Pye, Deborah, Kyriakouli, Dimitra S., Taylor, Geoffrey A., Johnson, Riem, Elstner, Matthias, Meunier, Brigitte, Chrzanowska-Lightowlers, Zofia M. A., Taylor, Robert W., Turnbull, Douglass M., Lightowlers, Robert N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2006
Schlagworte:
Methods Online
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1540737/
https://ncbi.nlm.nih.gov/pubmed/16885236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl516
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