Characterization of the Minimal DNA Binding Domain of the Human Papillomavirus E1 Helicase: Fluorescence Anisotropy Studies and Characterization of a Dimerization-Defective Mutant Protein

The E1 helicase of papillomaviruses is required for replication of the viral double-stranded DNA genome, in conjunction with cellular factors. DNA replication is initiated at the viral origin by the assembly of E1 monomers into oligomeric complexes that have unwinding activity. In vivo, this process...

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Main Authors: Titolo, S., Brault, K., Majewski, J., White, P. W., Archambault, J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Replication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC153954/
https://ncbi.nlm.nih.gov/pubmed/12692220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.9.5178-5191.2003
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