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Role of the ATP-Binding Domain of the Human Papillomavirus Type 11 E1 Helicase in E2-Dependent Binding to the Origin

Replication of the genome of human papillomaviruses (HPV) is initiated by the recruitment of the viral E1 helicase to the origin of DNA replication by the viral E2 protein, which binds specifically to the origin. We determined, for HPV type 11 (HPV-11), that the C-terminal 296 amino acids of E1 are...

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Detalhes bibliográficos
Main Authors: Titolo, Steve, Pelletier, Alex, Sauvé, Frédéric, Brault, Karine, Wardrop, Elizabeth, White, Peter W., Amin, Anthony, Cordingley, Michael G., Archambault, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC112583/
https://ncbi.nlm.nih.gov/pubmed/10364274
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