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Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by αvβ3 and α5β1 integrins

Tumstatin and endostatin are two inhibitors of angiogenesis derived from precursor human collagen molecules known as α3 chain of type IV collagen and α1 chain of type XVIII collagen, respectively. Although both these inhibitors are noncollagenous (NC1) domain fragments of collagens, they only share...

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Bibliografiske detaljer
Main Authors: Sudhakar, Akulapalli, Sugimoto, Hikaru, Yang, Changqing, Lively, Julie, Zeisberg, Michael, Kalluri, Raghu
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC153630/
https://ncbi.nlm.nih.gov/pubmed/12682293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0730882100
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