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Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by αvβ3 and α5β1 integrins

Tumstatin and endostatin are two inhibitors of angiogenesis derived from precursor human collagen molecules known as α3 chain of type IV collagen and α1 chain of type XVIII collagen, respectively. Although both these inhibitors are noncollagenous (NC1) domain fragments of collagens, they only share...

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Autors principals: Sudhakar, Akulapalli, Sugimoto, Hikaru, Yang, Changqing, Lively, Julie, Zeisberg, Michael, Kalluri, Raghu
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC153630/
https://ncbi.nlm.nih.gov/pubmed/12682293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0730882100
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