Φορτώνει......
Cytokines regulate postnatal hematopoietic stem cell expansion: opposing roles of thrombopoietin and LNK
The role of cytokines as regulators of hematopoietic stem cell (HSC) expansion remains elusive. Herein, we identify thrombopoietin (THPO) and the cytokine signaling inhibitor LNK, as opposing physiological regulators of HSC expansion. Lnk(−/−) HSCs continue to expand postnatally, up to 24-fold above...
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Κύριοι συγγραφείς: | , , , , , , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
Cold Spring Harbor Laboratory Press
2006
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1536053/ https://ncbi.nlm.nih.gov/pubmed/16882979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.385606 |
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