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Cyclooxygenase-1 and -2 enzymes differentially regulate the brain upstream NF-κB pathway and downstream enzymes involved in prostaglandin biosynthesis
We have recently reported that cyclooxygenase (COX)-2-deficiency affects brain upstream and downstream enzymes in the arachidonic acid (AA) metabolic pathway to prostaglandin E(2) (PGE(2)), as well as enzyme activity, protein and mRNA levels of the reciprocal isozyme, COX-1. To gain a better insight...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1534077/ https://ncbi.nlm.nih.gov/pubmed/16787416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2006.03926.x |
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