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Cyclooxygenase-1 and -2 enzymes differentially regulate the brain upstream NF-κB pathway and downstream enzymes involved in prostaglandin biosynthesis

We have recently reported that cyclooxygenase (COX)-2-deficiency affects brain upstream and downstream enzymes in the arachidonic acid (AA) metabolic pathway to prostaglandin E(2) (PGE(2)), as well as enzyme activity, protein and mRNA levels of the reciprocal isozyme, COX-1. To gain a better insight...

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Sonraí Bibleagrafaíochta
Main Authors: Choi, Sang-Ho, Langenbach, Robert, Bosetti, Francesca
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2006
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1534077/
https://ncbi.nlm.nih.gov/pubmed/16787416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2006.03926.x
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