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Cyclooxygenase-1 and -2 enzymes differentially regulate the brain upstream NF-κB pathway and downstream enzymes involved in prostaglandin biosynthesis

We have recently reported that cyclooxygenase (COX)-2-deficiency affects brain upstream and downstream enzymes in the arachidonic acid (AA) metabolic pathway to prostaglandin E(2) (PGE(2)), as well as enzyme activity, protein and mRNA levels of the reciprocal isozyme, COX-1. To gain a better insight...

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Detalhes bibliográficos
Main Authors: Choi, Sang-Ho, Langenbach, Robert, Bosetti, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1534077/
https://ncbi.nlm.nih.gov/pubmed/16787416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2006.03926.x
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