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The distinct roles of cyclooxygenase-1 and -2 in neuroinflammation: implications for translational research

Cyclooxygenases (COX-1 and COX-2) are key enzymes in the conversion of arachidonic acid to prostaglandins and other lipid mediators. Because it can be induced by inflammatory stimuli, COX-2 has been classically considered as the most appropriate target for anti-inflammatory drugs. However, recent da...

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Detalhes bibliográficos
Main Authors: Choi, Sang-Ho, Aid, Saba, Bosetti, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3379810/
https://ncbi.nlm.nih.gov/pubmed/19269697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2009.01.002
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