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The distinct roles of cyclooxygenase-1 and -2 in neuroinflammation: implications for translational research
Cyclooxygenases (COX-1 and COX-2) are key enzymes in the conversion of arachidonic acid to prostaglandins and other lipid mediators. Because it can be induced by inflammatory stimuli, COX-2 has been classically considered as the most appropriate target for anti-inflammatory drugs. However, recent da...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3379810/ https://ncbi.nlm.nih.gov/pubmed/19269697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2009.01.002 |
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