Differential gene expression patterns in cyclooxygenase-1 and cyclooxygenase-2 deficient mouse brain

BACKGROUND: Cyclooxygenase (COX)-1 and COX-2 produce prostanoids from arachidonic acid and are thought to have important yet distinct roles in normal brain function. Deletion of COX-1 or COX-2 results in profound differences both in brain levels of prostaglandin E(2 )and in activation of the transcr...

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Detalhes bibliográficos
Main Authors: Toscano, Christopher D, Prabhu, Vinaykumar V, Langenbach, Robert, Becker, Kevin G, Bosetti, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1839133/
https://ncbi.nlm.nih.gov/pubmed/17266762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-1-r14
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