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Altered mRNA Editing and Expression of Ionotropic Glutamate Receptors after Kainic Acid Exposure in Cyclooxygenase-2 Deficient Mice
Kainic acid (KA) binds to the AMPA/KA receptors and induces seizures that result in inflammation, oxidative damage and neuronal death. We previously showed that cyclooxygenase-2 deficient (COX-2(−/−)) mice are more vulnerable to KA-induced excitotoxicity. Here, we investigated whether the increased...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3093380/ https://ncbi.nlm.nih.gov/pubmed/21589914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019398 |
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