In Vitro Pharmacodynamic Evaluation of the Mutant Selection Window Hypothesis Using Four Fluoroquinolones against Staphylococcus aureus

To study the hypothesis of the mutant selection window (MSW) in a pharmacodynamic context, the susceptibility of a clinical isolate of methicillin-resistant Staphylococcus aureus exposed to moxifloxacin (MOX), gatifloxacin (GAT), levofloxacin (LEV), and ciprofloxacin (CIP) was tested daily by using...

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Detalhes bibliográficos
Main Authors: Firsov, Alexander A., Vostrov, Sergey N., Lubenko, Irene Y., Drlica, Karl, Portnoy, Yury A., Zinner, Stephen H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC153314/
https://ncbi.nlm.nih.gov/pubmed/12709329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.5.1604-1613.2003
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