Antistaphylococcal Effect Related to the Area under the Curve/MIC Ratio in an In Vitro Dynamic Model: Predicted Breakpoints versus Clinically Achievable Values for Seven Fluoroquinolones

Prediction of the relative efficacies of different fluoroquinolones is often based on the ratios of the clinically achievable area under the concentration-time curve (AUC) to the MIC, usually with incorporation of the MIC(50) or the MIC(90) and with the assumption of antibiotic-independent patterns...

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Bibliografiska uppgifter
Huvudupphovsmän: Firsov, Alexander A., Lubenko, Irene Y., Vostrov, Sergey N., Portnoy, Yury A., Zinner, Stephen H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2005
Ämnen:
Experimental Therapeutics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168651/
https://ncbi.nlm.nih.gov/pubmed/15980331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.7.2642-2647.2005
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