Autoinhibition of the Kit Receptor Tyrosine Kinase by the Cytosolic Juxtamembrane Region

Genetic studies have implicated the cytosolic juxtamembrane region of the Kit receptor tyrosine kinase as an autoinhibitory regulatory domain. Mutations in the juxtamembrane domain are associated with cancers, such as gastrointestinal stromal tumors and mastocytosis, and result in constitutive activ...

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Библиографические подробности

Опубликовано в::	Mol Cell Biol
Главные авторы:	Chan, Perry M., Ilangumaran, Subburaj, La Rose, Jose, Chakrabartty, Avijit, Rottapel, Robert
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Taylor & Francis 2003
Предметы:	Cell Growth and Development
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153186/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12697809/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.9.3067-3078.2003
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