Autoinhibition of the Kit Receptor Tyrosine Kinase by the Cytosolic Juxtamembrane Region

Genetic studies have implicated the cytosolic juxtamembrane region of the Kit receptor tyrosine kinase as an autoinhibitory regulatory domain. Mutations in the juxtamembrane domain are associated with cancers, such as gastrointestinal stromal tumors and mastocytosis, and result in constitutive activ...

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Podrobná bibliografie

Vydáno v:	Mol Cell Biol
Hlavní autoři:	Chan, Perry M., Ilangumaran, Subburaj, La Rose, Jose, Chakrabartty, Avijit, Rottapel, Robert
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 2003
Témata:	Cell Growth and Development
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153186/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12697809/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.9.3067-3078.2003
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