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Activation of the Erk Pathway Is Required for TGF-β1-Induced EMT In Vitro

Transforming growth factor-β1 (TGF-β1) can be tumorsuppressive through the activation of the Smadmediated signaling pathway. TGF-β1 can also enhance tumor progression by stimulating epithelial-tomesenchymal transition (EMT) through additional pathways. EMT is characterized by the acquisition of a fi...

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Detalhes bibliográficos
Main Authors: Xie, Lu, Law, Brian K, Chytil, Anna M, Brown, Kimberly A, Aakre, Mary E, Moses, Harold L
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1531665/
https://ncbi.nlm.nih.gov/pubmed/15548370
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