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Identification of Novel Smad2 and Smad3 Associated Proteins in Response to TGF-β1

Transforming growth factor-beta 1 (TGF-β1) is an important growth inhibitor of epithelial cells and insensitivity to this cytokine results in uncontrolled cell proliferation and can contribute to tumorigenesis. TGF-β1 signals through the TGF-β type I and type II receptors, and activates the Smad pat...

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Autors principals: Brown, Kimberly A., Ham, Amy-Joan L., Clark, Cara N., Meller, Nahum, Law, Brian K., Chytil, Anna, Cheng, Nikki, Pietenpol, Jennifer A., Moses, Harold L.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700048/
https://ncbi.nlm.nih.gov/pubmed/18729074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21860
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