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Abrogation of TGF-β signaling enhances chemokine production and correlates with prognosis in human breast cancer

In human breast cancer, loss of carcinoma cell–specific response to TGF-β signaling has been linked to poor patient prognosis. However, the mechanisms through which TGF-β regulates these processes remain largely unknown. In an effort to address this issue, we have now identified gene expression sign...

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Detalhes bibliográficos
Main Authors: Bierie, Brian, Chung, Christine H., Parker, Joel S., Stover, Daniel G., Cheng, Nikki, Chytil, Anna, Aakre, Mary, Shyr, Yu, Moses, Harold L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689133/
https://ncbi.nlm.nih.gov/pubmed/19451693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI37480
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