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TGF-β-induced RhoA and p160(ROCK) activation is involved in the inhibition of Cdc25A with resultant cell-cycle arrest

The ability of the transforming growth factor β (TGF-β) signaling pathways to inhibit proliferation of most cells while stimulating proliferation of others remains a conundrum. In this article, we report that the absence of RhoA and p160(ROCK) activity in fibroblastic NIH 3T3 cells and its presence...

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Detalhes bibliográficos
Main Authors: Bhowmick, Neil A., Ghiassi, Mayshan, Aakre, Mary, Brown, Kimberly, Singh, Vikas, Moses, Harold L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC307605/
https://ncbi.nlm.nih.gov/pubmed/14657354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2536483100
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