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p160ROCK mediates RhoA activation of Na-H exchange.
The ubiquitously expressed Na-H exchanger, NHE1, acts downstream of RhoA in a pathway regulating focal adhesion and actin stress fiber formation. p160ROCK, a serine/threonine protein kinase, is a direct RhoA target mediating RhoA-induced assembly of focal adhesions and stress fibers. Here, stress fi...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
1998
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1170800/ https://ncbi.nlm.nih.gov/pubmed/9707430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.16.4712 |
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