p160ROCK mediates RhoA activation of Na-H exchange.

The ubiquitously expressed Na-H exchanger, NHE1, acts downstream of RhoA in a pathway regulating focal adhesion and actin stress fiber formation. p160ROCK, a serine/threonine protein kinase, is a direct RhoA target mediating RhoA-induced assembly of focal adhesions and stress fibers. Here, stress fi...

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Bibliographic Details
Main Authors: Tominaga, T, Ishizaki, T, Narumiya, S, Barber, D L
Format: Artigo
Language:Inglês
Published: 1998
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170800/
https://ncbi.nlm.nih.gov/pubmed/9707430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/17.16.4712
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