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A rhodium(III) complex for high-affinity DNA base-pair mismatch recognition
A rhodium(III) complex, rac-[Rh(bpy)(2)phzi](3+) (bpy, 2,2′-bipyridine; phzi, benzo[a]phenazine-5,6-quinone diimine) has been designed as a sterically demanding intercalator targeted to destabilized mismatched sites in double-helical DNA. The complex is readily synthesized by condensation of the phe...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The National Academy of Sciences
2003
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC152991/ https://ncbi.nlm.nih.gov/pubmed/12610209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0537194100 |
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