Nucleotide-induced conformations in the neck region of dimeric kinesin

The neck region of kinesin constitutes a key component in the enzyme’s walking mechanism. Here we applied cryoelectron microscopy and image reconstruction to investigate the location of the kinesin neck in dimeric and monomeric constructs complexed to microtubules. To this end we enhanced the visibi...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Skiniotis, Georgios, Surrey, Thomas, Altmann, Stephan, Gross, Heinz, Song, Young-Hwa, Mandelkow, Eckhard, Hoenger, Andreas
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2003
Fag:	Articles
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152908/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12660159/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg164
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