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Nucleotide-induced conformations in the neck region of dimeric kinesin

The neck region of kinesin constitutes a key component in the enzyme’s walking mechanism. Here we applied cryoelectron microscopy and image reconstruction to investigate the location of the kinesin neck in dimeric and monomeric constructs complexed to microtubules. To this end we enhanced the visibi...

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Bibliografski detalji
Izdano u:EMBO J
Glavni autori: Skiniotis, Georgios, Surrey, Thomas, Altmann, Stephan, Gross, Heinz, Song, Young-Hwa, Mandelkow, Eckhard, Hoenger, Andreas
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2003
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152908/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12660159/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg164
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