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Nucleotide-induced conformations in the neck region of dimeric kinesin

The neck region of kinesin constitutes a key component in the enzyme’s walking mechanism. Here we applied cryoelectron microscopy and image reconstruction to investigate the location of the kinesin neck in dimeric and monomeric constructs complexed to microtubules. To this end we enhanced the visibi...

詳細記述

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書誌詳細
主要な著者: Skiniotis, Georgios, Surrey, Thomas, Altmann, Stephan, Gross, Heinz, Song, Young-Hwa, Mandelkow, Eckhard, Hoenger, Andreas
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2003
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC152908/
https://ncbi.nlm.nih.gov/pubmed/12660159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg164
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