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Nucleotide-induced conformations in the neck region of dimeric kinesin

The neck region of kinesin constitutes a key component in the enzyme’s walking mechanism. Here we applied cryoelectron microscopy and image reconstruction to investigate the location of the kinesin neck in dimeric and monomeric constructs complexed to microtubules. To this end we enhanced the visibi...

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書目詳細資料
發表在:EMBO J
Principais autores: Skiniotis, Georgios, Surrey, Thomas, Altmann, Stephan, Gross, Heinz, Song, Young-Hwa, Mandelkow, Eckhard, Hoenger, Andreas
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2003
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC152908/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12660159/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg164
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