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Microscopic evidence for a minus-end-directed power stroke in the kinesin motor ncd

We used cryo-electron microscopy and image reconstruction to investigate the structure and microtubule-binding configurations of dimeric non-claret disjunctional (ncd) motor domains under various nucleotide conditions, and applied molecular docking using ncd’s dimeric X-ray structure to generate a m...

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Autors principals: Wendt, Thomas G., Volkmann, Niels, Skiniotis, Georgios, Goldie, Kenneth N., Müller, Jens, Mandelkow, Eckhard, Hoenger, Andreas
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC137211/
https://ncbi.nlm.nih.gov/pubmed/12426369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf622
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