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WNK kinases regulate thiazide-sensitive Na-Cl cotransport

Pseudohypoaldosteronism type II (PHAII) is an autosomal dominant disorder of hyperkalemia and hypertension. Mutations in two members of the WNK kinase family, WNK1 and WNK4, cause the disease. WNK1 mutations are believed to increase WNK1 expression; the effect of WNK4 mutations remains unknown. The...

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書目詳細資料
Main Authors: Yang, Chao-Ling, Angell, Jordan, Mitchell, Rose, Ellison, David H.
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC152590/
https://ncbi.nlm.nih.gov/pubmed/12671053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317443
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