Single Nucleotide Polymorphisms in Genes Associated with Isoniazid Resistance in Mycobacterium tuberculosis

Isoniazid (INH) is a central component of drug regimens used worldwide to treat tuberculosis. Previous studies have identified resistance-associated mutations in katG, inhA, kasA, ndh, and the oxyR-ahpC intergenic region. DNA microarray-based experiments have shown that INH induces several genes in...

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Autores principales: Ramaswamy, Srinivas V., Reich, Robert, Dou, Shu-Jun, Jasperse, Linda, Pan, Xi, Wanger, Audrey, Quitugua, Teresa, Graviss, Edward A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Mechanisms of Resistance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC152487/
https://ncbi.nlm.nih.gov/pubmed/12654653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.4.1241-1250.2003
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