Polymorphisms in Isoniazid and Prothionamide Resistance Genes of the Mycobacterium tuberculosis Complex

Sequence analyses of 74 strains that encompassed major phylogenetic lineages of the Mycobacterium tuberculosis complex revealed 10 polymorphisms in mshA (Rv0486) and four polymorphisms in inhA (Rv1484) that were not responsible for isoniazid or prothionamide resistance. Instead, some of these mutati...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Projahn, Michaela, Köser, Claudio U., Homolka, Susanne, Summers, David K., Archer, John A. C., Niemann, Stefan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2011
Pynciau:
Mechanisms of Resistance
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165319/
https://ncbi.nlm.nih.gov/pubmed/21709103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00555-11
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