Polymorphisms in Isoniazid and Prothionamide Resistance Genes of the Mycobacterium tuberculosis Complex

Sequence analyses of 74 strains that encompassed major phylogenetic lineages of the Mycobacterium tuberculosis complex revealed 10 polymorphisms in mshA (Rv0486) and four polymorphisms in inhA (Rv1484) that were not responsible for isoniazid or prothionamide resistance. Instead, some of these mutati...

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Detalhes bibliográficos
Main Authors: Projahn, Michaela, Köser, Claudio U., Homolka, Susanne, Summers, David K., Archer, John A. C., Niemann, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165319/
https://ncbi.nlm.nih.gov/pubmed/21709103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00555-11
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