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Polymorphisms in Isoniazid and Prothionamide Resistance Genes of the Mycobacterium tuberculosis Complex

Sequence analyses of 74 strains that encompassed major phylogenetic lineages of the Mycobacterium tuberculosis complex revealed 10 polymorphisms in mshA (Rv0486) and four polymorphisms in inhA (Rv1484) that were not responsible for isoniazid or prothionamide resistance. Instead, some of these mutati...

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Détails bibliographiques
Auteurs principaux: Projahn, Michaela, Köser, Claudio U., Homolka, Susanne, Summers, David K., Archer, John A. C., Niemann, Stefan
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165319/
https://ncbi.nlm.nih.gov/pubmed/21709103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00555-11
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